Natural growth promoter chitosan oligosaccharide

RENGTY Chitosan oligosaccharide is natural alkaline oligosaccharides extracted from the shell of snow-crab and hydrolyzed chitosan by bio enzymolysis, it is a amino small molecules oligosaccharide with positive charge, whose molecular weight is under 3000DA, with good water-solubility, safe, nontoxic and easily absorbed by animal, because the chemical structure is very similar to plant fibers, it’s called edible animal cellulose.

Ключевые слова:

chitosan oligosaccharide chitosan oligosaccharide for pig chitosan oligosaccharide powder Natural growth promoter

Категория:

Application

Pig

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Susan.lee@rengty.com

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Запрос

Natural growth promoter chitosan oligosaccharide

Natural growth promoter chitosan oligosaccharide

Description

Chitosan oligosaccharide is a functional carbohydrate, which can be used as signal molecule, regulates the processes of immune, reproduction, diseases and so on. By the research of its structure, function, production and quality control, potimized and applied as feeds, drugs and vaccines, it can improve animal production performance, increase production efficiency and create economic value.

As a new feed additive, chitosan oligosaccharide can improve the production performance of pigs, poultry and aquatic animals, improve the immunity of the organism, and play the biological function of antibacterial and anti-inflammatory. It can be used as an effective substitute for feed antibiotics growth promoter, which opens up a new way for the development of new pollution-free green feed additives in feed industry.

Specification

Product name	Chitosan oligosaccharide
Key component	Chitosan oligosaccharide, maltodextrin
Appearance	Light yellow powder
Particle size	Residual is less than 0.5% on the standard sieve of 0.25mm
Glucosamine (NAG)	≥10%
Aroma	Sour odor
Water solubility	100% soluble in water
Moisture	≤10%
Ash	≤1.5%
Arsenic (As)	≤3.0 mg/kg
Plumbum (Pb)	≤5.0 mg/kg
Total plate count	≤2.0x10⁶ CFU/g
Total mould count	≤2.0x10⁴ CFU/g
Salmonella	Negative

Function

Anti-inflammatory, reduce the secretion of inflammatory factors, replace chlorotetracycline, reduce antibiotic dosage.
Improve animal antibody levels
Liver protection
Improve the reproductive performance of sows and increase the weight of weaning piglets.
Improve intestinal health, effectively prevent diarrhea in piglets, and improve the survival rate of piglets
Increase feed intake, improve feed conversion rate.

Availability in piglet trial

Effect of chitosan oligosaccharide on production performance of Piglet

Items	Control group	Test Group (500g/t)
Initial age (day)	21±2	21±1.5
Initial weight (Kg)	6.5±0.6	6.4±0.5
Final age (day)	70±2	70±1.5
Final weight (Kg)	27.3±0.7	29.9±0.8
Daily feed intake (g/d)	680±68	761±76
Daily gain (g/d)	421±80	479±69
FCR	1.62	1.59
Death rate (%)	4	1
Diarrhea rate (%)	9.8	4.5

Effect of chitosan oligosaccharide on immunity and intestinal micro ecological environment of Piglet

Items	Control group	Test Group (500g/t)
IgG (g/L)	2.01±0.17	2.50±0.13
IgA (g/L)	1.33±0.16	1.60±0.12
IgM (g/L)	3.80±0.11	4.12±0.12
T lymphocyte conversion rate	0.52±0.32	0.60±0.19
D0 intestinal lactobacillus (log cfu/g)	7.37±0.31	7.39±0.35
D21 intestinal lactobacillus (log cfu/g)	6.62±0.23	7.22±0.26
D0 intestinal E.coli (log cfu/g)	3.72±0.18	3.77±0.16
D21 intestinal E.coli (log cfu/g)	3.87±0.19	3.53±0.18

Reduce diarrhea rate of piglets, chitosan oligosaccharide (COS) replace chlorotetracycline

Effect of dietary chitosan oligosaccharide (COS) supplementation on diarrhea incidence and the fecal shedding of Escherichia coli and Lactobacillus (log cfu/g of weight digesta) in weaning pig8¹

Item	NC	Level of dietary COS (mg/kg)			PC	SEM	P-value
Item	NC	100	200	400	PC	SEM	P-value
Lactobacillus
d 0	7.37	7.34	7.39	7.40	7.42	0.16	0.820
d 7	6.88	7.05	7.10	7.07	6.94	0.24	0.190
d 14	6.72^b	7.07^a	7.11^a	7.06^a	6.65^b	0.40	0.009
d 21	6.62^b	7.15^a	7.22^a	7.13^a	6.66^b	0.52	0.010
E.coli
d 0	3.72	3.74	3.77	3.75	3.78	0.14	0.891
d 7	3.87	3.68	3.65	3.69	3.55	0.28	0.162
d 14	3.95	3.56	3.53	3.58	3.38	0.46	0.082
d 21	3.87^a	3.57^ab	3.53^b	3.62^ab	3.38^b	0.36	0.035
Diarrhea incidence, ^z %	13.8^a	6.7^b	6.2^b	9.0^b	5.7^b		<0.05
Diarrhea score, ^z %	19^a	9^b	8^b	10^b	8^b		<0.05

^ab Means in the same row with different superscripts differ (P<0.05)

¹ values are of 10 individually caged pig8 (3 replicates per pig). NC=pigs in the negative control group were fed the basal diet. PC=pigs in the positive control group were fed the basal diet supplemented with 80 mg/kg of chlorotetracycline.

Availability in sow trial

Effect of chitosan oligosaccharide on parturition performance of pregnant sow

Items	Control group	Test Group (500g/t)
Litter size	10.5±0.64	12.3±0.5
Survival Littermate	9.8±0.5	11.7±0.4
Healthy Littermate	8.9±0.4	11.2±0.4
Weight at birth per litter	14.0±0.9	18.4±0.6
Weight at birth per piglet	1.5±0.04	1.7±0.04
Daily gain (g/d)	421±80	479±69
FCR	1.62	1.59
Death rate (%)	4	1
Diarrhea rate (%)	9.8	4.5

Effect of chitosan oligosaccharide on production performance of lactating sow

Items		Control group	Test Group (500g/t)
D1 weight per piglet		1.56±0.04	1.66±0.03
D12	Weight per litter	36.9±1.7	44.1±1.1
	D1-12 weight gain per litter	22.5±1.4	26.0±0.8
	Weight per piglet	4.28±0.13	4.5±0.08
	D1-12 weight gain per piglet	0.226±0.01	0.237±0.01
D21	Weight per litter	55.5±2.4	68.1±2.2
	D12-21 weight gain per litter	33.0±1.6	42.0±1
	D1-21 weight gain per litter per day	1.96±0.09	2.38±0.09
	Weight per piglet	6.5±0.2	7.0±0.1
	D12-21 weight gain per piglet	0.25±0.01	0.28±0.01
	D1-21 weight gain per piglet	0.237±0.009	0.256±0.006

Recommended dosage

Animal	Stage	Dosage (g/t)	Stage	Dosage (g/t)
Piglet	5-30 kg	300-500	30-100 kg	200-400
Sow	Pre-pregnancy	300-500	Late pregnancy-mating	300

Packaging and Storage

Sample	20g/bag, 200g/bag, 300g/bag, 500g/bag, 1kg/bag, 2kg/bag, 5kg/bag
Packaging	20kg/bag, 20kg/drum or as requirements.
Pallet	If 20kg/bag, 1000kg/50bag/pallet
Container	One 20'GP can contain 10-14 tons if bag
Storage	Stored 24 months sealed in a cool, dry and airy place